Severe dynein dysfunction in cholinergic neurons exacerbates ALS-like phenotypes in a new mouse model
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1871 (1). https://doi.org/10.1016/j.bbadis.2024.167540
Fabio A. Simoes, Eleni Christoforidou, Raphaelle Cassel, Luc Dupuis and Majid Hafezparast.
Publications
2024
Patient-specific computational models predict prognosis in B cell lymphoma by quantifying pro-proliferative and anti-apoptotic signatures from genetic sequencing data
Blood Cancer Journal 14 (105). https://doi.org/10.1038/s41408-024-01090-y
Richard Norris, John Jones, Erika Mancini, Timothy Chevassut, Fabio A. Simoes, Chris Pepper, Andrea Pepper and Simon Mitchell
2024
2024
An ALS-Associated Mutation Dysregulates Microglia-Derived Extracellular MicroRNAs in a Sex-Specific Manner.
Disease Models & Mechanisms 17 (5). https://doi.org/10.1242/dmm.050638
Eleni Christoforidou, Libby Moody, Greig Joilin, Fabio A Simoes, David Gordon, Kevin Talbot, and Majid Hafezparast.
Aberrant Dynein Function Promotes TDP-43 Aggregation and Upregulation of P62 in Male Mice Harboring Transgenic Human TDP-43.
Frontotemporal Degeneration 24 (7–8): 746–55. https://doi.org/10.1080/21678421.2023.2239276
Eleni Christoforidou, Fabio A Simoes, David Gordon, Kevin Talbot, and Majid Hafezparast.
2023
Potential of Non-Coding RNA as Biomarkers for Progressive Supranuclear Palsy.
International Journal of Molecular Sciences 23 (23): 14554. https://doi.org/10.3390/ijms232314554
Fabio A. Simoes, Greig Joilin, Oliver Peters, Luisa-Sophie Schneider, Josef Priller, Eike Jakob Spruth, Ina Vogt, Okka Kimmich, Annika Spottke, and Daniel C Hoffmann.
2022
Drosophila TDP-43 Dysfunction in Glia and Muscle Cells Cause Cytological and Behavioural Phenotypes That Characterize ALS and FTLD.
Human Molecular Genetics 22 (19): 3883–93. https://doi.org/10.1093/hmg/ddt243
Diaper, Danielle C, Yoshitsugu Adachi, Luke Lazarou, Max Greenstein, Fabio A Simoes, Angelique di Domenico, Daniel A Solomon, Simon Lowe, Rawan Alsubaie, and Daryl Cheng.